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Automated Analysis of Time-Lapse Imaging of Nuclear Translocation by Retrospective Strategy and Its Application to STAT1 in HeLa Cells

Cell-based image analysis of time-lapse imaging is mainly challenged by faint fluorescence and dim boundaries of cellular structures of interest. To resolve these bottlenecks, a novel method was developed based on “retrospective” analysis for cells undergoing minor morphological changes during time-...

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Detalles Bibliográficos
Autores principales: Han, Fujun, Liang, Peizhou, Wang, Feifei, Zeng, Lingyun, Zhang, Biliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220678/
https://www.ncbi.nlm.nih.gov/pubmed/22125613
http://dx.doi.org/10.1371/journal.pone.0027454