Coordinated Defects in Hepatic Long Chain Fatty Acid Metabolism and Triglyceride Accumulation Contribute to Insulin Resistance in Non-Human Primates

Non-Alcoholic fatty liver disease (NAFLD) is characterized by accumulation of triglycerides (TG) in hepatocytes, which may also trigger cirrhosis. The mechanisms of NAFLD are not fully understood, but insulin resistance has been proposed as a key determinant. AIMS: To determine the TG content and lo...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamath, Subhash, Chavez, Alberto O., Gastaldelli, Amalia, Casiraghi, Francesca, Halff, Glenn A., Abrahamian, Gregory A., Davalli, Alberto M., Bastarrachea, Raul A., Comuzzie, Anthony G., Guardado-Mendoza, Rodolfo, Jimenez-Ceja, Lilia M., Mattern, Vicki, Paez, Ana Maria, Ricotti, Andrea, Tejero, Mary E., Higgins, Paul B., Rodriguez-Sanchez, Iram Pablo, Tripathy, Devjit, DeFronzo, Ralph A., Dick, Edward J., Cline, Gary W., Folli, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220682/
https://www.ncbi.nlm.nih.gov/pubmed/22125617
http://dx.doi.org/10.1371/journal.pone.0027617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220682/
https://www.ncbi.nlm.nih.gov/pubmed/22125617
http://dx.doi.org/10.1371/journal.pone.0027617

Ejemplares similares