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The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo

There are several lines of evidence pointing towards the importance of β-oxidation in host survival of Mycobacterium tuberculosis including enormous gene redundancy for this process; approximately 100 genes are annotated as β-oxidation genes for the five biochemical reactions that break down fatty a...

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Detalles Bibliográficos
Autores principales: Williams, Kerstin J., Boshoff, Helena I., Krishnan, Nitya, Gonzales, Jacqueline, Schnappinger, Dirk, Robertson, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Churchill Livingstone 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220763/
https://www.ncbi.nlm.nih.gov/pubmed/21764638
http://dx.doi.org/10.1016/j.tube.2011.06.006