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Differential Effects of Adiposity on Pharmacodynamics of Basal Insulins NPH, Glargine, and Detemir in Type 2 Diabetes Mellitus

OBJECTIVE: To assess the role of adiposity on the pharmacodynamics of basal insulins NPH, detemir, and glargine in type 2 diabetes mellitus (T2DM), as estimated by glucose infusion rate (GIR) and endogenous glucose production (EGP) rate in the euglycemic clamp. RESEARCH DESIGN AND METHODS: We examin...

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Detalles Bibliográficos
Autores principales: Porcellati, Francesca, Lucidi, Paola, Rossetti, Paolo, Candeloro, Paola, Marinelli Andreoli, Anna, Marzotti, Stefania, Cioli, Patrizia, Bolli, Geremia B., Fanelli, Carmine G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220859/
https://www.ncbi.nlm.nih.gov/pubmed/21972412
http://dx.doi.org/10.2337/dc11-1064