HPV-16 E1, E2 and E6 each complement the Ad5 helper gene set, increasing rAAV2 and wt AAV2 production

Adeno-associated virus type 2 (AAV) is a popular vector for human gene therapy, because of its safety record and ability to express genes long term. Yet large scale recombinant (r)AAV production remains problematic due to low particle yield. The adenovirus (Ad) and herpes (simplex) virus (HSV) helpe...

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Detalles Bibliográficos
Autores principales: Cao, M., Zhu, H., Bandyopadhyay, S, You, H, Hermonat, P.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220924/
https://www.ncbi.nlm.nih.gov/pubmed/21850053
http://dx.doi.org/10.1038/gt.2011.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220924/
https://www.ncbi.nlm.nih.gov/pubmed/21850053
http://dx.doi.org/10.1038/gt.2011.115

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