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Fuel-Stimulated Insulin Secretion Depends upon Mitochondria Activation and the Integration of Mitochondrial and Cytosolic Substrate Cycles
The pancreatic islet β-cell is uniquely specialized to couple its metabolism and rates of insulin secretion with the levels of circulating nutrient fuels, with the mitochondrial playing a central regulatory role in this process. In the β-cell, mitochondrial activation generates an integrated signal...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Korean Diabetes Association
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221020/ https://www.ncbi.nlm.nih.gov/pubmed/22111036 http://dx.doi.org/10.4093/dmj.2011.35.5.458 |