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Protective Effect of Heme Oxygenase-1 on High Glucose-Induced Pancreatic β-Cell Injury
BACKGROUND: Glucose toxicity that is caused by chronic exposure to a high glucose concentration leads to islet dysfunction and induces apoptosis in pancreatic β-cells. Heme oxygenase-1 (HO-1) has been identified as an anti-apoptotic and cytoprotective gene. The purpose of this study is to investigat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221022/ https://www.ncbi.nlm.nih.gov/pubmed/22111038 http://dx.doi.org/10.4093/dmj.2011.35.5.469 |