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Protective Effect of Heme Oxygenase-1 on High Glucose-Induced Pancreatic β-Cell Injury

BACKGROUND: Glucose toxicity that is caused by chronic exposure to a high glucose concentration leads to islet dysfunction and induces apoptosis in pancreatic β-cells. Heme oxygenase-1 (HO-1) has been identified as an anti-apoptotic and cytoprotective gene. The purpose of this study is to investigat...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Mi, Lee, Young-Eun, Lee, Esder, Ryu, Gyeong Ryul, Ko, Seung-Hyun, Moon, Sung-Dae, Song, Ki-Ho, Ahn, Yu-Bae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221022/
https://www.ncbi.nlm.nih.gov/pubmed/22111038
http://dx.doi.org/10.4093/dmj.2011.35.5.469