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Mycobacterial P(1)-Type ATPases Mediate Resistance to Zinc Poisoning in Human Macrophages

Mycobacterium tuberculosis thrives within macrophages by residing in phagosomes and preventing them from maturing and fusing with lysosomes. A parallel transcriptional survey of intracellular mycobacteria and their host macrophages revealed signatures of heavy metal poisoning. In particular, mycobac...

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Detalles Bibliográficos
Autores principales: Botella, Hélène, Peyron, Pascale, Levillain, Florence, Poincloux, Renaud, Poquet, Yannick, Brandli, Irène, Wang, Chuan, Tailleux, Ludovic, Tilleul, Sylvain, Charrière, Guillaume M., Waddell, Simon J., Foti, Maria, Lugo-Villarino, Geanncarlo, Gao, Qian, Maridonneau-Parini, Isabelle, Butcher, Philip D., Castagnoli, Paola Ricciardi, Gicquel, Brigitte, de Chastellier, Chantal, Neyrolles, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221041/
https://www.ncbi.nlm.nih.gov/pubmed/21925112
http://dx.doi.org/10.1016/j.chom.2011.08.006