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Mycobacterial P(1)-Type ATPases Mediate Resistance to Zinc Poisoning in Human Macrophages
Mycobacterium tuberculosis thrives within macrophages by residing in phagosomes and preventing them from maturing and fusing with lysosomes. A parallel transcriptional survey of intracellular mycobacteria and their host macrophages revealed signatures of heavy metal poisoning. In particular, mycobac...
Autores principales: | Botella, Hélène, Peyron, Pascale, Levillain, Florence, Poincloux, Renaud, Poquet, Yannick, Brandli, Irène, Wang, Chuan, Tailleux, Ludovic, Tilleul, Sylvain, Charrière, Guillaume M., Waddell, Simon J., Foti, Maria, Lugo-Villarino, Geanncarlo, Gao, Qian, Maridonneau-Parini, Isabelle, Butcher, Philip D., Castagnoli, Paola Ricciardi, Gicquel, Brigitte, de Chastellier, Chantal, Neyrolles, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221041/ https://www.ncbi.nlm.nih.gov/pubmed/21925112 http://dx.doi.org/10.1016/j.chom.2011.08.006 |
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