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A DNA Vaccine Encoding for TcSSP4 Induces Protection against Acute and Chronic Infection in Experimental Chagas Disease

Immunization of mice with plasmids containing genes of Trypanosoma cruzi induces protective immunity in the murine model of Chagas disease. A cDNA clone that codes for an amastigote-specific surface protein (TcSSP4) was used as a candidate to develop a DNA vaccine. Mice were immunized with the recom...

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Detalles Bibliográficos
Autores principales: Arce-Fonseca, Minerva, Ramos-Ligonio, Angel, López-Monteón, Aracely, Salgado-Jiménez, Berenice, Talamás-Rohana, Patricia, Rosales-Encina, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221361/
https://www.ncbi.nlm.nih.gov/pubmed/22110377