Attenuation of Cytotoxic Natural Product DNA Intercalating Agents by Caffeine

Many anti-tumor drugs function by intercalating into DNA. The xanthine alkaloid caffeine can also intercalate into DNA as well as form π-π molecular complexes with other planar alkaloids and anti-tumor drugs. The presence of caffeine could interfere with the intercalating anti-tumor drug by forming...

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Detalles Bibliográficos
Autores principales: Hill, Gabrielle M., Moriarity, Debra M., Setzer, William N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221498/
https://www.ncbi.nlm.nih.gov/pubmed/22145102
http://dx.doi.org/10.3797/scipharm.1107-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221498/
https://www.ncbi.nlm.nih.gov/pubmed/22145102
http://dx.doi.org/10.3797/scipharm.1107-19

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