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Attenuation of Cytotoxic Natural Product DNA Intercalating Agents by Caffeine
Many anti-tumor drugs function by intercalating into DNA. The xanthine alkaloid caffeine can also intercalate into DNA as well as form π-π molecular complexes with other planar alkaloids and anti-tumor drugs. The presence of caffeine could interfere with the intercalating anti-tumor drug by forming...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Österreichische Apotheker-Verlagsgesellschaft
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221498/ https://www.ncbi.nlm.nih.gov/pubmed/22145102 http://dx.doi.org/10.3797/scipharm.1107-19 |