Prediction of the Human EP1 Receptor Binding Site by Homology Modeling and Molecular Dynamics Simulation

The prostanoid receptor EP1 is a G-protein-coupled receptor (GPCR) known to be involved in a variety of pathological disorders such as pain, fever and inflammation. These receptors are important drug targets, but design of subtype specific agonists and antagonists has been partially hampered by the...

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Detalles Bibliográficos
Autores principales: Zare, Behnoush, Madadkar-Sobhani, Armin, Dastmalchi, Siavoush, Mahmoudian, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221501/
https://www.ncbi.nlm.nih.gov/pubmed/22145106
http://dx.doi.org/10.3797/scipharm.1106-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221501/
https://www.ncbi.nlm.nih.gov/pubmed/22145106
http://dx.doi.org/10.3797/scipharm.1106-24

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