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Simple, Rapid and Validated LC Determination of Lopinavir in Rat Plasma and its Application in Pharmacokinetic Studies

Lopinavir is a new specific and potent HIV-1 protease inhibitor. A simple and rapid Reverse Phase High-Performance Liquid Chromatographic method using UV detection was developed and validated for the analysis of lopinavir in rat plasma under isocratic conditions. The method involves a single step pr...

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Detalles Bibliográficos
Autores principales: Vats, Rahul, Murthy, Aditya Narasimha, Ravi, Punna Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221505/
https://www.ncbi.nlm.nih.gov/pubmed/22145109
http://dx.doi.org/10.3797/scipharm.1107-24