Capturing Alzheimer's disease genomes with induced pluripotent stem cells: prospects and challenges

A crucial limitation to our understanding of Alzheimer's disease (AD) is the inability to test hypotheses on live, patient-specific neurons. Patient autopsies are limited in supply and only reveal endpoints of disease. Rodent models harboring familial AD mutations lack important pathologies, an...

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Detalles Bibliográficos
Autores principales: Israel, Mason A, Goldstein, Lawrence SB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221547/
https://www.ncbi.nlm.nih.gov/pubmed/21867573
http://dx.doi.org/10.1186/gm265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221547/
https://www.ncbi.nlm.nih.gov/pubmed/21867573
http://dx.doi.org/10.1186/gm265

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