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Optically Mapping Multiple Bacterial Genomes Simultaneously in a Single Run

Optical mapping of bacterial chromosomes provides an unambiguous low-resolution sequence scaffold of the entire chromosome. In comparison to some techniques, such as pulse field gel electrophoresis, cost and throughput limit the application of this technique outside of genome finishing. We have demo...

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Detalles Bibliográficos
Autores principales: Riley, Matthew C., Lee, James Eric, Lesho, Emil, Kirkup, Benjamin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221658/
https://www.ncbi.nlm.nih.gov/pubmed/22132087
http://dx.doi.org/10.1371/journal.pone.0027085