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Molecular Evolution of the Transmembrane Domains of G Protein-Coupled Receptors
G protein-coupled receptors (GPCRs) are a superfamily of integral membrane proteins vital for signaling and are important targets for pharmaceutical intervention in humans. Previously, we identified a group of ten amino acid positions (called key positions), within the seven transmembrane domain (7T...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221663/ https://www.ncbi.nlm.nih.gov/pubmed/22132149 http://dx.doi.org/10.1371/journal.pone.0027813 |