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The Mechanism of Enhanced Insulin Amyloid Fibril Formation by NaCl Is Better Explained by a Conformational Change Model

The high propensity of insulin to fibrillate causes severe biomedical and biotechnological complications. Insulin fibrillation studies attain significant importance considering the prevalence of diabetes and the requirement of functional insulin in each dose. Although studied since the early years o...

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Detalles Bibliográficos
Autores principales: Muzaffar, Mahvish, Ahmad, Atta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221682/
https://www.ncbi.nlm.nih.gov/pubmed/22132167
http://dx.doi.org/10.1371/journal.pone.0027906