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The Anticancer Plant Triterpenoid, Avicin D, Regulates Glucocorticoid Receptor Signaling: Implications for Cellular Metabolism

Avicins, a family of apoptotic triterpene electrophiles, are known to regulate cellular metabolism and energy homeostasis, by targeting the mitochondria. Having evolved from “ancient hopanoids,” avicins bear a structural resemblance with glucocorticoids (GCs), which are the endogenous regulators of...

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Detalles Bibliográficos
Autores principales: Haridas, Valsala, Xu, Zhi-Xiang, Kitchen, Doug, Jiang, Anna, Michels, Peter, Gutterman, Jordan U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221683/
https://www.ncbi.nlm.nih.gov/pubmed/22132201
http://dx.doi.org/10.1371/journal.pone.0028037