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The Anticancer Plant Triterpenoid, Avicin D, Regulates Glucocorticoid Receptor Signaling: Implications for Cellular Metabolism
Avicins, a family of apoptotic triterpene electrophiles, are known to regulate cellular metabolism and energy homeostasis, by targeting the mitochondria. Having evolved from “ancient hopanoids,” avicins bear a structural resemblance with glucocorticoids (GCs), which are the endogenous regulators of...
Autores principales: | Haridas, Valsala, Xu, Zhi-Xiang, Kitchen, Doug, Jiang, Anna, Michels, Peter, Gutterman, Jordan U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221683/ https://www.ncbi.nlm.nih.gov/pubmed/22132201 http://dx.doi.org/10.1371/journal.pone.0028037 |
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