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Non-Invasive Imaging of Cysteine Cathepsin Activity in Solid Tumors Using a (64)Cu-Labeled Activity-Based Probe

The papain family of cysteine cathepsins are actively involved in multiple stages of tumorigenesis. Because elevated cathepsin activity can be found in many types of human cancers, they are promising biomarkers that can be used to target radiological contrast agents for tumor detection. However, cur...

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Detalles Bibliográficos
Autores principales: Ren, Gang, Blum, Galia, Verdoes, Martijn, Liu, Hongguang, Syed, Salahuddin, Edgington, Laura E., Gheysens, Olivier, Miao, Zheng, Jiang, Han, Gambhir, Sanjiv Sam, Bogyo, Matthew, Cheng, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221694/
https://www.ncbi.nlm.nih.gov/pubmed/22132198
http://dx.doi.org/10.1371/journal.pone.0028029