Cargando…
Non-Invasive Imaging of Cysteine Cathepsin Activity in Solid Tumors Using a (64)Cu-Labeled Activity-Based Probe
The papain family of cysteine cathepsins are actively involved in multiple stages of tumorigenesis. Because elevated cathepsin activity can be found in many types of human cancers, they are promising biomarkers that can be used to target radiological contrast agents for tumor detection. However, cur...
Autores principales: | Ren, Gang, Blum, Galia, Verdoes, Martijn, Liu, Hongguang, Syed, Salahuddin, Edgington, Laura E., Gheysens, Olivier, Miao, Zheng, Jiang, Han, Gambhir, Sanjiv Sam, Bogyo, Matthew, Cheng, Zhen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221694/ https://www.ncbi.nlm.nih.gov/pubmed/22132198 http://dx.doi.org/10.1371/journal.pone.0028029 |
Ejemplares similares
-
Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer
por: Edgington-Mitchell, Laura E., et al.
Publicado: (2015) -
Comparative Assessment of Substrates and Activity Based Probes as Tools for Non-Invasive Optical Imaging of Cysteine Protease Activity
por: Blum, Galia, et al.
Publicado: (2009) -
Cathepsin Activity-Based Probes and Inhibitor for Preclinical Atherosclerosis Imaging and Macrophage Depletion
por: Abd-Elrahman, Ihab, et al.
Publicado: (2016) -
Inhibitory prodrug mechanism for cysteine cathepsin-targeted self-controlled drug release
por: van Dalen, Floris J., et al.
Publicado: (2022) -
Cathepsin B trafficking in thyroid carcinoma cells
por: Tedelind, Sofia, et al.
Publicado: (2011)