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Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients
INTRODUCTION: Studies on the role of programmed death-1(PD-1) and its main ligand (PD-L1) during experimental models of sepsis have shown that the PD-1/PD-L1 pathway plays a pathologic role in altering microbial clearance, the innate inflammatory response and accelerated apoptosis in sepsis. However...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222003/ https://www.ncbi.nlm.nih.gov/pubmed/21349174 http://dx.doi.org/10.1186/cc10059 |