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HCCS1-armed, quadruple-regulated oncolytic adenovirus specific for liver cancer as a cancer targeting gene-viro-therapy strategy

BACKGROUND: In previously published studies, oncolytic adenovirus-mediated gene therapy has produced good results in targeting cancer cells. However, safety and efficacy, the two most important aspects in cancer therapy, remain serious challenges. The specific expression or deletion of replication r...

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Detalles Bibliográficos
Autores principales: Xu, Hai-Neng, Huang, Wei-Dan, Cai, Ying, Ding, Miao, Gu, Jin-Fa, Wei, Na, Sun, Lan-Ying, Cao, Xin, Li, Hua-Guang, Zhang, Kang-Jian, Liu, Xin-Ran, Liu, Xin-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222618/
https://www.ncbi.nlm.nih.gov/pubmed/22040050
http://dx.doi.org/10.1186/1476-4598-10-133