QTL Analysis Identifies a Modifier Locus of Aganglionosis in the Rat Model of Hirschsprung Disease Carrying Ednrb(sl) Mutations

Hirschsprung disease (HSCR) exhibits complex genetics with incomplete penetrance and variable severity thought to result as a consequence of multiple gene interactions that modulate the ability of enteric neural crest cells to populate the developing gut. As reported previously, when the same null m...

Descripción completa

Detalles Bibliográficos
Autores principales: Dang, Ruihua, Torigoe, Daisuke, Sasaki, Nobuya, Agui, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222640/
https://www.ncbi.nlm.nih.gov/pubmed/22132166
http://dx.doi.org/10.1371/journal.pone.0027902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222640/
https://www.ncbi.nlm.nih.gov/pubmed/22132166
http://dx.doi.org/10.1371/journal.pone.0027902

Ejemplares similares