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HIV gp120 Binds to Mannose Receptor on Vaginal Epithelial Cells and Induces Production of Matrix Metalloproteinases

BACKGROUND: During sexual transmission of HIV in women, the virus breaches the multi-layered CD4 negative stratified squamous epithelial barrier of the vagina, to infect the sub-epithelial CD4 positive immune cells. However the mechanisms by which HIV gains entry into the sub-epithelial zone is hith...

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Detalles Bibliográficos
Autores principales: Fanibunda, Sashaina E., Modi, Deepak N., Gokral, Jyotsna S., Bandivdekar, Atmaram H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222676/
https://www.ncbi.nlm.nih.gov/pubmed/22132194
http://dx.doi.org/10.1371/journal.pone.0028014