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Direct Lineage Conversions: Unnatural but useful?

Classic experiments such as somatic cell nuclear transfer into oocytes or cell fusion demonstrated that differentiated cells are not irreversibly committed to their fate. More recent work has built on these conclusions and discovered defined factors that directly induce one specific cell type from a...

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Detalles Bibliográficos
Autores principales: Vierbuchen, Thomas, Wernig, Marius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222779/
https://www.ncbi.nlm.nih.gov/pubmed/21997635
http://dx.doi.org/10.1038/nbt.1946