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Assessment of Hypoxia Inducible Factor Levels in Cancer Cell Lines upon Hypoxic Induction Using a Novel Reporter Construct

Hypoxia Inducible Factor (HIF) signaling pathway is important for tumor cells with limited oxygen supplies, as it is shown to be involved in the process of proliferation and angiogenesis. Given its pivotal role in cancer biology, robust assays for tracking changes in HIF expression are necessary for...

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Detalles Bibliográficos
Autores principales: Zhou, Wenyu, Dosey, Timothy L., Biechele, Travis, Moon, Randall T., Horwitz, Marshall S., Ruohola-Baker, Hannele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223176/
https://www.ncbi.nlm.nih.gov/pubmed/22132102
http://dx.doi.org/10.1371/journal.pone.0027460