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Lithium Monotherapy Increases ACTH and Cortisol Response in the Dex/CRH Test in Unipolar Depressed Subjects. A Study with 30 Treatment-Naive Patients

BACKGROUND: Distorted activity of the hypothalamic-pituitary-adrenocortical (HPA) system is one of the most robustly documented biological abnormalities in major depression. Lithium is central to the treatment of affective disorders, but little is known about its effects on the HPA system of depress...

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Detalles Bibliográficos
Autores principales: Bschor, Tom, Ritter, Dirk, Winkelmann, Patricia, Erbe, Sebastian, Uhr, Manfred, Ising, Marcus, Lewitzka, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223180/
https://www.ncbi.nlm.nih.gov/pubmed/22132117
http://dx.doi.org/10.1371/journal.pone.0027613