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Identification of Cytotoxic Drugs That Selectively Target Tumor Cells with MYC Overexpression

Expression of MYC is deregulated in a wide range of human cancers, and is often associated with aggressive disease and poorly differentiated tumor cells. Identification of compounds with selectivity for cells overexpressing MYC would hence be beneficial for the treatment of these tumors. For this pu...

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Detalles Bibliográficos
Autores principales: Frenzel, Anna, Zirath, Hanna, Vita, Marina, Albihn, Ami, Henriksson, Marie Arsenian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223192/
https://www.ncbi.nlm.nih.gov/pubmed/22132187
http://dx.doi.org/10.1371/journal.pone.0027988