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Identification of Cytotoxic Drugs That Selectively Target Tumor Cells with MYC Overexpression
Expression of MYC is deregulated in a wide range of human cancers, and is often associated with aggressive disease and poorly differentiated tumor cells. Identification of compounds with selectivity for cells overexpressing MYC would hence be beneficial for the treatment of these tumors. For this pu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223192/ https://www.ncbi.nlm.nih.gov/pubmed/22132187 http://dx.doi.org/10.1371/journal.pone.0027988 |