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The Recognition of N-Glycans by the Lectin ArtinM Mediates Cell Death of a Human Myeloid Leukemia Cell Line

ArtinM, a d-mannose-binding lectin from Artocarpus heterophyllus (jackfruit), interacts with N-glycosylated receptors on the surface of several cells of hematopoietic origin, triggering cell migration, degranulation, and cytokine release. Because malignant transformation is often associated with alt...

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Detalles Bibliográficos
Autores principales: Carvalho, Fernanda Caroline, Soares, Sandro Gomes, Tamarozzi, Mirela Barros, Rego, Eduardo Magalhães, Roque-Barreira, Maria-Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223207/
https://www.ncbi.nlm.nih.gov/pubmed/22132163
http://dx.doi.org/10.1371/journal.pone.0027892