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Mutations in the Catalytic Loop HRD Motif Alter the Activity and Function of Drosophila Src64
The catalytic loop HRD motif is found in most protein kinases and these amino acids are predicted to perform functions in catalysis, transition to, and stabilization of the active conformation of the kinase domain. We have identified mutations in a Drosophila src gene, src64, that alter the three HR...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223231/ https://www.ncbi.nlm.nih.gov/pubmed/22132220 http://dx.doi.org/10.1371/journal.pone.0028100 |