In Vitro Effects of Pirfenidone on Cardiac Fibroblasts: Proliferation, Myofibroblast Differentiation, Migration and Cytokine Secretion

Cardiac fibroblasts (CFs) are the primary cell type responsible for cardiac fibrosis during pathological myocardial remodeling. Several studies have illustrated that pirfenidone (5-methyl-1-phenyl-2-[1H]-pyridone) attenuates cardiac fibrosis in different animal models. However, the effects of pirfen...

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Detalles Bibliográficos
Autores principales: Shi, Qiang, Liu, Xiaoyan, Bai, Yuanyuan, Cui, Chuanjue, Li, Jun, Li, Yishi, Hu, Shengshou, Wei, Yingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223242/
https://www.ncbi.nlm.nih.gov/pubmed/22132230
http://dx.doi.org/10.1371/journal.pone.0028134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223242/
https://www.ncbi.nlm.nih.gov/pubmed/22132230
http://dx.doi.org/10.1371/journal.pone.0028134

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