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Localized Aurora B activity spatially controls non-kinetochore microtubules during spindle assembly

Efficient spindle assembly involves the generation of spatial cues around chromosomes that locally stabilize microtubule (MT) plus-ends. In addition to the small GTPase Ran, there is evidence that Aurora B kinase might also generate a spatial cue around chromosomes but direct proof for this is still...

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Detalles Bibliográficos
Autores principales: Tanenbaum, Marvin E., Medema, René H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223347/
https://www.ncbi.nlm.nih.gov/pubmed/21786106
http://dx.doi.org/10.1007/s00412-011-0334-9