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Protein stability: a single recorded mutation aids in predicting the effects of other mutations in the same amino acid site
Motivation: Accurate prediction of protein stability is important for understanding the molecular underpinnings of diseases and for the design of new proteins. We introduce a novel approach for the prediction of changes in protein stability that arise from a single-site amino acid substitution; the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223369/ https://www.ncbi.nlm.nih.gov/pubmed/21998155 http://dx.doi.org/10.1093/bioinformatics/btr576 |