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State-of-the-Art Automated Patch Clamp Devices: Heat Activation, Action Potentials, and High Throughput in Ion Channel Screening

Ion channels are essential in a wide range of cellular functions and their malfunction underlies many disease states making them important targets in drug discovery. The availability of standardized cell lines expressing ion channels of interest lead to the development of diverse automated patch cla...

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Detalles Bibliográficos
Autores principales: Stoelzle, Sonja, Obergrussberger, Alison, Brüggemann, Andrea, Haarmann, Claudia, George, Michael, Kettenhofen, Ralf, Fertig, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223389/
https://www.ncbi.nlm.nih.gov/pubmed/22131976
http://dx.doi.org/10.3389/fphar.2011.00076