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Exogenous interleukin-6, interleukin-13, and interferon-gamma provoke pulmonary abnormality with mild edema in enterovirus 71-infected mice

BACKGROUND: Neonatal mice developed neurological disease and pulmonary dysfunction after an infection with a mouse-adapted human Enterovirus 71 (EV71) strain MP4. However, the hallmark of severe human EV71 infection, pulmonary edema (PE), was not evident. METHODS: To test whether EV71-induced PE req...

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Detalles Bibliográficos
Autores principales: Huang, Szu-Wei, Lee, Yi-Ping, Hung, Yu-Ting, Lin, Chun-Hung, Chuang, Jih-Ing, Lei, Huan-Yao, Su, Ih-Jen, Yu, Chun-Keung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223501/
https://www.ncbi.nlm.nih.gov/pubmed/22054060
http://dx.doi.org/10.1186/1465-9921-12-147