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Macrophage-Elicited Loss of Estrogen Receptor Alpha in Breast Cancer Cells via Involvement of MAPK and c-Jun at the ESR1 Genomic Locus

Estrogen receptor alpha (ERα, ESR1) is a pivotal transcriptional regulator of breast cancer physiology and is targeted by endocrine therapies. Loss of ERα activity or expression is an indication of endocrine resistance and is associated with increased risk of tumor recurrence and worse prognosis. In...

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Detaylı Bibliyografya
Asıl Yazarlar: Stossi, Fabio, Madak-Erdoğan, Zeynep, Katzenellenbogen, Benita S.
Materyal Türü: Online Makale Metin
Dil:English
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223561/
https://www.ncbi.nlm.nih.gov/pubmed/21860415
http://dx.doi.org/10.1038/onc.2011.370