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Macrophage-Elicited Loss of Estrogen Receptor Alpha in Breast Cancer Cells via Involvement of MAPK and c-Jun at the ESR1 Genomic Locus

Estrogen receptor alpha (ERα, ESR1) is a pivotal transcriptional regulator of breast cancer physiology and is targeted by endocrine therapies. Loss of ERα activity or expression is an indication of endocrine resistance and is associated with increased risk of tumor recurrence and worse prognosis. In...

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Detalles Bibliográficos
Autores principales:	Stossi, Fabio, Madak-Erdoğan, Zeynep, Katzenellenbogen, Benita S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223561/ https://www.ncbi.nlm.nih.gov/pubmed/21860415 http://dx.doi.org/10.1038/onc.2011.370

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