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Disruption of a mitochondrial protease machinery in Plasmodium falciparum is an intrinsic signal for parasite cell death

The ATP-dependent ClpQY protease system in Plasmodium falciparum is a prokaryotic machinery in the parasite. In the present study, we have identified the complete ClpQY system in P. falciparum and elucidated its functional importance in survival and growth of asexual stage parasites. We characterize...

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Detalles Bibliográficos
Autores principales: Rathore, S, Jain, S, Sinha, D, Gupta, M, Asad, M, Srivastava, A, Narayanan, M S, Ramasamy, G, Chauhan, V S, Gupta, D, Mohmmed, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223699/
https://www.ncbi.nlm.nih.gov/pubmed/22113196
http://dx.doi.org/10.1038/cddis.2011.118