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Estimating developmental states of tumors and normal tissues using a linear time-ordered model

BACKGROUND: Tumor cells are considered to have an aberrant cell state, and some evidence indicates different development states appearing in the tumorigenesis. Embryonic development and stem cell differentiation are ordered processes in which the sequence of events over time is highly conserved. The...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Chen, Beibei, Wu, Tao, Xuan, Zhenyu, Zhu, Xiaopeng, Chen, Runsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223864/
https://www.ncbi.nlm.nih.gov/pubmed/21310084
http://dx.doi.org/10.1186/1471-2105-12-53