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Estimating developmental states of tumors and normal tissues using a linear time-ordered model
BACKGROUND: Tumor cells are considered to have an aberrant cell state, and some evidence indicates different development states appearing in the tumorigenesis. Embryonic development and stem cell differentiation are ordered processes in which the sequence of events over time is highly conserved. The...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223864/ https://www.ncbi.nlm.nih.gov/pubmed/21310084 http://dx.doi.org/10.1186/1471-2105-12-53 |