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QTc prolongation assessment in anticancer drug development: clinical and methodological issues
Cardiac safety assessments are commonly employed in the clinical development of investigational oncology medications. In anti-cancer drug development there has been increasing consideration for the potential of a compound to cause adverse electrocardiographic changes, especially QT interval prolonga...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cancer Intelligence
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223992/ https://www.ncbi.nlm.nih.gov/pubmed/22275999 http://dx.doi.org/10.3332/ecancer.2009.130 |