Somatic retrotransposition alters the genetic landscape of the human brain

Retrotransposons are mobile genetic elements that employ a germ line “copy-and-paste” mechanism to spread throughout metazoan genomes(1). At least 50% of the human genome is derived from retrotransposons, with three active families (L1, Alu and SVA) associated with insertional mutagenesis and diseas...

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Detalles Bibliográficos
Autores principales: Baillie, J. Kenneth, Barnett, Mark W., Upton, Kyle R., Gerhardt, Daniel J., Richmond, Todd A., De Sapio, Fioravante, Brennan, Paul, Rizzu, Patrizia, Smith, Sarah, Fell, Mark, Talbot, Richard T., Gustincich, Stefano, Freeman, Thomas C., Mattick, John S., Hume, David A., Heutink, Peter, Carninci, Piero, Jeddeloh, Jeffrey A., Faulkner, Geoffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224101/
https://www.ncbi.nlm.nih.gov/pubmed/22037309
http://dx.doi.org/10.1038/nature10531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224101/
https://www.ncbi.nlm.nih.gov/pubmed/22037309
http://dx.doi.org/10.1038/nature10531

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