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Proportion statistics to detect differentially expressed genes: a comparison with log-ratio statistics

BACKGROUND: In genetic transcription research, gene expression is typically reported in a test sample relative to a reference sample. Laboratory assays that measure gene expression levels, from Q-RT-PCR to microarrays to RNA-Seq experiments, will compare two samples to the same genetic sequence of i...

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Detalles Bibliográficos
Autores principales: Bergemann, Tracy L, Wilson, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224106/
https://www.ncbi.nlm.nih.gov/pubmed/21649912
http://dx.doi.org/10.1186/1471-2105-12-228