Assessing pooled BAC and whole genome shotgun strategies for assembly of complex genomes

BACKGROUND: We investigate if pooling BAC clones and sequencing the pools can provide for more accurate assembly of genome sequences than the "whole genome shotgun" (WGS) approach. Furthermore, we quantify this accuracy increase. We compare the pooled BAC and WGS approaches using in silico...

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Detalles Bibliográficos
Autores principales: Haiminen, Niina, Feltus, F Alex, Parida, Laxmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224119/
https://www.ncbi.nlm.nih.gov/pubmed/21496274
http://dx.doi.org/10.1186/1471-2164-12-194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224119/
https://www.ncbi.nlm.nih.gov/pubmed/21496274
http://dx.doi.org/10.1186/1471-2164-12-194

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