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Assessing pooled BAC and whole genome shotgun strategies for assembly of complex genomes
BACKGROUND: We investigate if pooling BAC clones and sequencing the pools can provide for more accurate assembly of genome sequences than the "whole genome shotgun" (WGS) approach. Furthermore, we quantify this accuracy increase. We compare the pooled BAC and WGS approaches using in silico...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224119/ https://www.ncbi.nlm.nih.gov/pubmed/21496274 http://dx.doi.org/10.1186/1471-2164-12-194 |