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Immortalized cells and one oncogene in malignant transformation: old insights on new explanation

BACKGROUND: Nearly thirty years ago, it was first shown that malignant transformation with single oncogene necessarily requires the immortal state of the cell. From that time this thesis for the cells of human origin was not disproved. The basic point which we want to focus on by this short communic...

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Detalles Bibliográficos
Autores principales: Kavsan, Vadym M, Iershov, Anton V, Balynska, Olena V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224126/
https://www.ncbi.nlm.nih.gov/pubmed/21605454
http://dx.doi.org/10.1186/1471-2121-12-23