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An integrated approach identifies IFN-regulated microRNAs and targeted mRNAs modulated by different HCV replicon clones

BACKGROUND: Infections with hepatitis C virus (HCV) progress to chronic phase in 80% of patients. To date, the effect produced by HCV on the expression of microRNAs (miRs) involved in the interferon-β (IFN-β) antiviral pathway has not been explored in details. Thus, we compared the expression profil...

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Detalles Bibliográficos
Autores principales: Bruni, Roberto, Marcantonio, Cinzia, Tritarelli, Elena, Tataseo, Paola, Stellacci, Emilia, Costantino, Angela, Villano, Umbertina, Battistini, Angela, Ciccaglione, Anna Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224138/
https://www.ncbi.nlm.nih.gov/pubmed/21970718
http://dx.doi.org/10.1186/1471-2164-12-485